Clinical Pathology

Amniocentesis test procedure, purpose

Amniocentesis is a medical procedure used primarily in prenatal diagnosis to sample and analyze amniotic fluid surrounding a fetus in the uterus.

This fluid contains fetal cells and various chemicals produced by the baby, allowing healthcare providers to detect genetic disorders, chromosomal abnormalities.

It is commonly performed during the second trimester, usually between 15 and 20 weeks of pregnancy. Here is the Amniocentesis test procedure steps.

  • An ultrasound is conducted to confirm the baby’s position, locate the amniotic sac, and identify a safe spot for needle insertion.
  • The abdomen is cleansed with an antiseptic solution to reduce the risk of infection.
  • Guided by ultrasound, a thin, hollow needle is carefully inserted through the abdominal wall, into the uterus, and into the amniotic sac.
  • A small amount of amniotic fluid (usually around 20 mL) is drawn into a syringe. This fluid contains fetal cells that can be analyzed.
  • We performe following tests Karyotyping, Genetic Testing for Single-Gene Disorders, Alpha-Fetoprotein (AFP) Testing, Alpha-Fetoprotein (AFP) Testing and Rh Incompatibility.

What is the purpose of Amniocentesis test?

  • Identifying conditions like Down syndrome, cystic fibrosis, and spina bifida.
  • Assessing fetal lung maturity.
  • Testing for severe anemia if there’s a risk of Rh incompatibility.
  • Early detecting infections.
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