Categories: Hematology

what are the differences between serum and plasma (serum vs plasma)

Difference between serum and plasma

Following are the differences between serum and plasma.

  • The serum is fluid.
  • Fibrinogen absent
  • It obtains after blood clotting.
  • It is used for blood typing and diagnostic purposes also.
  1. Plasma is also liquid.
  2. It contains fibrinogen.
  3. Obtains before the coagulation process.
  4. It is used to diagnose blood clotting diseases, thrombin time, partial thromboplastin time, and prothrombin time.
SerumPlasma
The serum is fluid.Plasma is liquid.
Fibrinogen absentIt contains fibrinogen.
It obtains after blood clotting.Obtains before the coagulation process.
It is used for blood typing and diagnostic purposes also. Study the Blood clotting disease.
Difference between serum and plasma

what is serum in blood?

The substance which comes out after blood clotting is serum.

  1. It lacks Clotting factors.
  2. It lacks fibrinogen protein.

What is plasma in blood?

Plasma makes up about 55% of the overall blood volume.

  1. plasma also contains fibrinogen (which contributes to the normal clotting of blood) and albumin (which keeps fluid in your bloodstream and prevents leaking into other tissues).
  2. The plasma in the blood is to transport all the proteins, nutrients, antibodies, hormones, etc.
  3. As the plasma races around the body, cells will deposit their waste into the plasma, which contributes to another job of the plasma: waste removal

what is the difference between plasma and blood?

The difference between plasma and blood is that blood consists of all kinds of blood cells like Red blood cells, White blood cells, platelets, fibrinogen, and other clotting factors.

When blood is centrifuged, all kinds of blood cells (RBC, WBC, platelets except fibrinogen and clotting factors) are separated by centrifugal force. A clear watery type of liquid came out. This is known as plasma.

Note: Blood consists of 55% Plasma.

what are the similarities between serum and plasma?

There are a few similarities between serum and plasma.

  1. Both are in clear form.
  2. Both can be used for diagnosis purposes (Typhoid, malaria, HBV, HCV)
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