Hematology is the branch of medicine focused on the study of blood, blood-forming organs, and related disorders. It includes the diagnosis and treatment of conditions such as:
Hematologists use specialized tests like complete blood counts (CBC) and bone marrow analysis to provide accurate diagnoses and effective treatments.
ABO blood group system was discovered by Karle Lanstiner in 1901. After a few years, other blood types like Rh, Kell, Kidd, Duffy, Lewis, Lutheran, and MNS were identified. It is important abo blood grouping methods to screen blood groups in the blood banks. There are two abo blood grouping methods in the blood bank. … Read more
Coomb test or anti-globulin test is an important test in blood bank. Coomb’s test has two types dirct coomb test and indirect coomb test. This test is used assess the sensitized red blood cell. RBC sensitized by the IgG antibodies or by the complements. How many types of coomb test in blood bank? There are … Read more
Indirect Coombs test or indirect antiglobulin test is a type of coombs test, it is an important test for the detection of circulating antibodies in the plasma, which do not agglutinate cells suspended in the saline. It depends on the combination of in vitro of an antibody with its specific antigen. Indirect Coombs test principle … Read more
Direct antiglobulin test or direct Coomb’s test is an important test for the diagnosis of haemolytic disease in newborns. Sometimes IgG sensitizes the RBC but it cannot produce agglutination. Due to the small size of IgG, it is unable to overcome the force that causes rbc to repel one another, resulting in a failing cross-linked … Read more
Difference between serum and plasma Following are the differences between serum and plasma. Serum Plasma The serum is fluid. Plasma is liquid. Fibrinogen absent It contains fibrinogen. It obtains after blood clotting. Obtains before the coagulation process. It is used for blood typing and diagnostic purposes also. Study the Blood clotting disease. Difference between … Read more
Thrombin is an important enzyme in the coagulation pathway. The thrombin time principle is simply that, this enzyme changes the fibrinogen into fibrin in the coagulation pathway. Time spend during clot formation after the addition of Thrombin is called Thrombin time. Thrombin time test Requirement: procedure for the thrombin time What is the Reference Range … Read more
Leishman stain is a commonly used stain in the hematology lab. It is used to identify the white blood cells, malaria parasite, cutaneous leishmania, and Trypanosoma species. Leishman stain preparation Requirements Following are the requirements of Leishman stain preparation. Leishman stain procedure
A platelet count blood test is important for the calculation of platelet in the blood. Like other blood tests Hb, CBC, LFT (liver function test), RFT (Renal function test), and platelet can be counted by two methods. Note: Both methods are used but the manual or visual method is more reliable than an electronic particle … Read more
Mostly white blood cells (WBC) or TLC are calculated by an automated hematology analyzer but WBC can be calculated by the formula for WBC count in the Neubauer chamber (TLC test). WBC / TLC count Principle Anticoagulated blood mixed with diluting fluid in a WBC pipette. After mixing the charge in the Neubauer chamber. Count … Read more
Anemia is defined as a low hemoglobin level. There are three types of anemia. Microcytic hypochromic anemia is one of the most occurring types. Signs, symptoms, and lab diagnosis of microcytic hypochromic anemia is different from other kinds of anemia. Clinical Laboratory finding in microcytic hypochromic anemia Following are the lab finding in microcytic hypochromic … Read more