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A liver function test (LFT test) is an important test for measuring a particular biomarker in the blood. It helps in the
- Diagnosis of liver disease
- monitoring therapy,
- assessing the prognosis.
Here’s the video of Liver function test normal range chart (LFT test), Alt, Ast, Alp, albumin, total protein.
There are two groups of tests used to assess the liver disease.
- Routine LFT
- Special LFT
Routine Liver Function Test (LFT) name
Routine LFTs include six serum (S) tests.
- Serum alanine aminotransferase (ALT or SGPT )
- Serum Alkaline phosphatase (ALP)
- Serum Bilirubin
- Total protein and Albumin
- S. Gamma-glutamyl transferase (GGT)
- S. 5-Nucleotidase
- Serum Ammonia
NOTE: Serum albumin range shows the synthetic function of the liver. while bilirubin indicated the excretory function of the liver. ALT and AST are directly linked to liver damage. The rest of the test, GGT, ALP, and 5- nucleotidase relates to liver obstruction.
What are the Specials liver function Test name in cirrhosis liver
Following are the six special LFT tests.
- Serum iron and copper
- Alpha-fetoprotein
- Hepatitis Markers
- Prothrombin time
- Blood ammonia
- Liver biopsy
Serum total Bilirubin | 3-17 micromol/litter | |||||
Alanine aminotransferase (ALT) | up to 42 u/l | |||||
Asparatate amino transferase(AST) | up to 37 u/l | |||||
Serum Alkaline Phosphatase (ALP) | 60-306 u/l | |||||
Total Protein | 60-80 g/l | |||||
Albumin | 40-50 g/l | |||||
Gamma Glutamyltransferase GGT | 11- 60 u/l |
when to worry about alt levels?
Liver function tests rise when the hepatocyte is damaged by the pathogen. When is minor damage, there will be a mild change in ALT, AST, and bilirubin. But when there is severe liver damage, the following changes will occur.
- ALT will be more than 42 U/litter.
- AST will be higher than 37 U/litter.
- Serum Albumin is less than 65 g/l.
Can a liver function test detect cancer?
A liver function test can detect damaged liver cells. When there is a malignancy or infiltration, the following LFT test value alters.
- Aminotransferase (ALA) will increase
- Alkaline Phosphatase (ALP) will raise.
- Albumin can be decreased or normal
- Prothrombin, Bilirubin, GGT all these tests will be normal.
will the liver function test show liver damage?
The answer to this question is YES. ALT and AST enzyme range in the serum is directly linked to hepatocytes. When liver cells are attacked by any kind of pathogen like HBV or HCV, alanine aminotransferase and aspartate aminotransferase rises.
Can a liver function test detect cirrhosis?
Yes, a liver function test (LFT test) can detect cirrhosis. Cirrhosis is the end stage of liver disease. At this stage, the liver stops its synthesis and neutralizing functions.
At this stage, albumin decreases, and ALT, AST, bilirubin, ALP, and GGT ranges will increase.
Can liver function tests be normal with liver disease?
Liver function tests can be normal with liver disease, but IF the disease is at its initial stage and it did not damage more liver cells, in the late stage, ALT (SGPT), and AST, will raise in the blood.
What is Liver function test ALT ??
ALT is the short-term for alanine aminotransferase. ALT is a special test for detecting hepatic cell damage. ALT and AST levels tend to increase during the onset of viral attacks.
Liver function test ( AST normal range)
Aspartate aminotransferase (AST) normal is between 0 to 37 micro/litter.
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Does a liver function test require fasting?
In most cases, no fasting is required for liver function tests (LFT tests). But some laboratories asked for fasting before collecting LFT test samples.
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Can a liver function test detect cancer?
A liver function test can detect damaged liver cells. When there is a malignancy or infiltration, the following LFT test value changes.
1. ALT will be more than 42 U/litter.
2. AST will be higher than 37 U/litter.
3. Serum Albumin is less than 65 g/l. -
When did LFT test values increase?
Liver function tests range (serum bilirubin, ALT, AST, GGT, ALP) directly link hepatocyte function. When liver cells are damaged due to the virus (HBV, HCV ) results in the elevation of liver function test.
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When to worry about alt levels?
Liver function tests rise when the hepatocyte is damaged by the pathogen. When is mid-damage, there will be a mild change in ALT, AST, and bilirubin. But when their severe damage, AST, and SGPT values will be more than 45 ul.
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What is the alkaline phosphatase (ALP) normal range?
The alkaline phosphatase normal range is 60-306 u/l.
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What is Ggt’s normal range?
GGT stands for Gamma Glutamyl transferase. The ggt normal range is 11- 60 u/l
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Total protein normal range?
60-80 g/l total protein normal range.
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Alkaline phosphatase normal range in males/females?
Alkaline phosphatase normal range in males/females 60-306 u/l.
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what is a normal alt level?
The normal ALT level is typically considered to be less than 40 units per liter (U/L) for males and less than 32 U/L for females
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what is a hepatic function panel?
A hepatic function panel, also known as a liver function test or liver panel, is a blood test that evaluates the health and function of the liver.
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what level of ggt is dangerous?
A high level of gamma-glutamyl transferase (GGT) in the blood can indicate liver damage or disease.Significantly elevated GGT levels above the normal range (typically exceeding 3 times the upper limit) may indicate liver dysfunction.
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what is ast and alt?
AST stands for Aspartate Aminotransferase, while ALT stands for Alanine Aminotransferase. These are enzymes found mainly in the liver, but they are also present in other organs like the heart, muscles, and kidneys.
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how long should i abstain from alcohol before a liver function test?
It’s generally advised to abstain from alcohol for 24 to 48 hours before a liver function test.
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