Systemic lupus erythematosus symptoms,causes diagnosis, rashes

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that affects multiple organs and systems in the body.

It is characterized by the production of antibodies that attack healthy tissues, leading to inflammation and tissue damage.

What are the signs and symptoms of Systemic lupus erythematosus?

The signs and symptoms of systemic lupus erythematosus (SLE) can vary greatly and range from mild to severe. Some common signs and symptoms include:

  • Skin rashes: A distinctive skin rash, known as a butterfly rash, can occur on the face and is often one of the first signs of SLE. Other skin rashes may also occur.
  • Joint pain and swelling: Inflammation and pain in the joints, particularly in the hands, feet, and wrists, is a common symptom of SLE.
  • Fever: SLE can cause frequent low-grade fevers, which may be accompanied by fatigue and weakness.
  • Fatigue: SLE can cause severe fatigue and weakness, making it difficult to carry out daily activities.
  • Sensitivity to light: SLE can cause sensitivity to light, particularly in the eyes.
  • Chest pain: SLE can cause chest pain or discomfort, particularly during deep breathing.
  • Mouth sores: SLE can cause painful mouth sores, particularly on the gums and in the throat.
  • Neurological symptoms: SLE can cause neurological symptoms, such as confusion, memory loss, and seizures.
  • Kidney problems: SLE can cause kidney problems, such as inflammation and damage, which can lead to kidney failure.

What are the causes of Systemic lupus erythematosus?

Following are the possible causes of systemic lupus erythematosus.

  • Environmental triggers: Exposure to certain environmental triggers, such as UV light, viruses, or certain drugs, may trigger the development of SLE in people who have a genetic predisposition.
  • Genetics: SLE is known to run in families, and people with a family history of the disease have an increased risk of developing it.
  • Hormonal factors: Hormonal changes, such as those that occur during pregnancy or the menstrual cycle, can trigger the onset or worsening of SLE symptoms in some people.
  • Immune system: SLE is an autoimmune disease, which means that the body’s immune system mistakenly attacks healthy tissue. This can lead to inflammation and tissue damage throughout the body.
  • Infections: Certain infections, such as Epstein-Barr virus or hepatitis C, have been linked to the development of SLE.

Note: The exact cause of systemic lupus erythematosus (SLE) is unknown.

What are the diagnosis of lupus erythematosus?

Following are the possible diagnosis of systemic lupus erythematosus.

  • Photosensitivity
  • Positive ANA (anti-nuclear antibody) Test
  • Low RBC and white blood cell counts
  • Abnormal levels of proteins and/or cells in the blood
  • Rash (butterfly-shaped on the face)

What are the skin symptoms of autoimmune Systemic Lupus?

Following are the skin symptoms of SLE.

  • Rash, especially the “butterfly” rash on the face.
  • Purplish or reddish patches on the skin.
  • Lesions that worsen with sun exposure (photosensitivity)
  • Subcutaneous lupus erythematosus (painful nodules under the skin)
  • Discoid lupus erythematosus (raised, scaly, coin-shaped lesions)

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